The 28th Discovery Science Conference and other co-located events will be held under the common umbrella name AI for Science. The International Conference Discovery Science (DS) has a long tradition, as this edition will be the 28th in a row. It was previously held in Slovenia as an independent organization by the Slovenian Institute of Science (IJS). The meeting is intended for discussions and exchange of ideas among researchers who develop and use methods of artificial intelligence (AI), data science and big data analysis in solving scientific and industrial challenges. Due to the importance of the topic, we will also organize a series of thematic tracks related to AI in various scientific disciplines. Some of them will preform under the sponsorship of SMASH.